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Among them, mono-AEEA and tri-AEEA originate from the starting material di-AEEA, while β-Ala is formed as a by-product via a Lossen rearrangement that occurs during the activation and deprotection steps
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Drugs hold a different nucleus moiety which demonstrates contrast in physical and chemical properties, but also observed in seldom studies that 5th and 6th membered rings like piperazine, piperidine, pyrazine, xanthine, pyrrolidine, thiazolidine and thiosemicarbazide, bicyclic ring, and adamantane are some commonly used scaffolds that has shown anti-diabetic activity by amplifying incretin effects
